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As busy health professionals, it is challenging to keep up with current literature about cord blood banking. Insception is dedicated to helping you stay up-to-date on with the latest developments so that your patients can make informed decisions about cord blood banking.
Outcomes after related and unrelated umbilical cord blood transplantation for hereditary bone marrow failure syndromes other than Fanconi anemia
Studied the effectiveness of Cord blood stems cells for patients with hereditary bone marrow failure syndromes, related umbilical cord blood transplantation is associated with excellent outcomes while increasing cell dose and better HLA matching might provide better results in unrelated umbilical cord blood transplantation.
Lifetime probabilities of hematopoietic stem cell transplantation in the U.S.
Discussions of current indications, the lifetime probability of undergoing autologous or allogeneic HSCT is much higher than previously reported by others and could rise even higher with increases in donor availability and HSCT applicability.
Results of the Cord Blood Transplantation Study (COBLT)
This article presents the clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies.
Umbilical cord blood transplantation for acute myeloid leukemia
The aid of this study is to discuss the recent advances in the field of umbilical cord blood (UCB) transplant (UCBT) for the treatment of adult acute myeloid leukemia.
Expanding the role of umbilical cord blood transplantation
This article reviews the state of the art and future directions with umbilical cord blood as a source of haematopoietic stem cells for transplantation in both children and adults.
Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome
Improved outcomes from early transplantation and immediate availability of cord blood units lead us to conclude that cord blood transplantation is a beneficial option, which should be considered expediently for children with Hurler's Syndrome.
Emerging trends in transplantation of inherited metabolic diseases
Allogeneic hematopoietic stem cell transplantation (HSCT) can prolong life and improve its quality in patients with inherited metabolic diseases.
This review will summarize the findings reported in the literature with regards to the use of CB stem cells to neurological applications including in vitro work, pre-clinical animal studies, and patient clinical trials.
Neural progenitors, neurons and oligodendrocytes from human umbilical cord blood cells in a serum-free, feeder-free cell culture
The objective of this study was to determine the optimal conditions required for Lin(neg) UCB cells to differentiate into neuronal cells and oligodendrocytes.
Identification and analysis of in vitro cultured CD45-positive cells capable of multi-lineage differentiation
We report on a subset of cells that co-purify with CD45-positive/Lineage minus (CD45(pos)/Lin(minus)) hematopoietic cells that are capable of in vitro differentiation into multi-potential cells including cells with neuroectoderm properties.
High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years
Because long-term cryopreservation is critical for CB banking and transplantation, we assessed the efficiency of recovery of viable HSC/HPC from individual CBs stored frozen for 15 yr.
