Expanded access to cord blood therapy for cerebral palsy and autism patients



Expanded access to cord blood therapy for cerebral palsy and autism patients

Expanded access to cord blood therapy for cerebral palsy and autism patients

Children with various brain disorders, such as autism and cerebral palsy, who have their own or a sibling’s cord blood stored in a family bank may now be able to receive cord blood therapy.

The cord blood therapy is being provided by Duke University Medical Centre under an expanded access clinical trial granted by the US Food and Drug Administration (FDA).

It is estimated that thousands of children around the world may be eligible for this breakthrough treatment1.

Clinical trials around the world are showing encouraging results in the use of cord blood for neurological conditions such as cerebral palsy and autism. Studies to date have demonstrated positive trends in improvement in gross motor function and social cognition. Further studies are underway around the world to add to the mounting evidence.

In light of the mounting evidence, the expanded access program is designed to enable children with various brain disorders to be infused with autologous cord blood (a patient’s own) or sibling’s cord bloodoutside of clinical trials.

Conditions/Diseases Listed in the Study2

  • Autism Spectrum Disorder
  • Cerebral Palsy
  • Hydrocephalus
  • Apraxia of Speech
  • Hypoxia Ischemia, Cerebral
  • Drowning; Anoxia

The expanded access program is utilizing safety and efficacy data from clinical trials at Duke University Medical Centre in which some 700 patients with a listed condition/disease were infused with autologous or sibling umbilical cord blood over the past decade2.

As outlined in the study details, children with a brain injury covered by the study “will be eligible if they do not qualify for or are unable to participate in another active clinical trial at Duke. Children with qualifying partially or fully matched sibling or autologous cord blood units will be eligible.”

Over 1 in 68 children in Canada are diagnosed with some level of autism and approximately 60,000 Canadians are living with cerebral palsy.  With such prevalence of neurological disorders covered by the expanded access protocol, this new therapy designation signals a promising step forward for the use of both autologous and sibling cord blood in regenerative medicine.

Further details on the study description, eligibility criteria, contacts and locations can be found here.

If you have a child with cerebral palsy and are pregnant, you may be eligible for Insception Lifebank’s Cerebral Palsy Cord Blood Collection Program.


Insception Lifebank offers free cord blood collection and storage for newborn babies who have a sibling with cerebral palsy.

The Cerebral Palsy Cord Blood Collection Program aims to ensure as many families of children with cerebral palsy as possible have access to potential local and international cord blood trials.

The program is open to a limited number of participants. Families wishing to participate are required to meet the following eligibility criteria.

  • You must be expecting a child and have a child diagnosed with cerebral palsy. The child diagnosed with cerebral palsy must:
    • Be under 12 years of age
    • Have a confirmed diagnosis of cerebral palsy
    • Have the same biological parents as the expected child
    • Other criteria apply

Please contact Client Services at 1 (866) 606-2790 or info@insception.com if you would like further information on our Cerebral Palsy Sibling Cord Blood Collection Program.

Expectant parents are encouraged to learn more about their cord blood and tissue storage options.



  1. Retrieved 15th January, 2018, from https://celltrials.org/news/featured-advanced-cell-therapy-trial-expanded-access-cord-blood-therapy-autism-and-cerebral-palsy
  2. Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries, NCT03327467, https://clinicaltrials.gov/ct2/show/NCT03327467